Tuesday, December 8, 2015

Chronic Pain, Fibromyalgia, & Depression Research


Fibromyalgia is a widespread non-inflammatory pain syndrome with multi-system manifestations, and occurs primarily in females between the ages of 20-65 years old. Fibromyalgia in the adult US population prevalence is between 1-2%.1 The condition appears to be a primary disorder of pain processing, or central sensitization. Risk factors include female sex, poor functional status, stressful life events and low socioeconomic status.  Comorbid conditions that frequently occur with fibromyalgia include depression, rheumatologic conditions, and both inflammatory and non-inflammatory disorders. 

Chronic pain symptoms are often experienced for many years, if not indefinitely, for most patients experiencing chronic pain, which is economically exhaustive to the patient and population. Long-term treatment outcomes from a multi-disciplinary care approach shows evidence of a significant decrease in the psychological symptoms of depression, anxiety, and physical pain.2 Determinants of extended duration of treatment outcome appear to be a result of the environment in which treatment occurs, such as individual versus group treatment.  This treatment approach supports the idea that a multi-disciplinary care offers an improved treatment outcome compared to standard of care for chronic pain. Research suggests that the physician or practitioner-patient relationship is central to treatment success and is reflected in an international case conference of integrative medicine for the treatment of chronic pain.3 

Mindfulness and meditative practices have demonstrated improvement in quality of life, including depression in patients diagnosed with fibromyalgia.3 Research demonstrated that mindfulness had a greater benefit than the control interventions (mindfulness-based stress reduction without training), and the intervention had long lasting effects for females with fibromyalgia.4
 

1. Domino, Frank J. The 5-minute Clinical Consult Standard. Philadelphia, PA: Wolters Kluwer Health; 2015. 444-445 p.

2.Meineche-Schmidet V, Jensen N.H, Sjogren P.  Long-term outcome of multidisciplinary intervention of chronic pain patients in a private setting.  Scandinavian Journal of Pain.  2012; 3: 99-105.


3.Benno Rehberg.  Evidence-Based integrative pain medicine.  European Journal of Integrative Medicine. 2010; 3:109-113.


4.Grossman P, Tiefenthaler-Gilmer U, Raysz A, Kesper U. Mindfulness training as an intervention for fibromyalgia: Evidence of postintervention and 3-year follow-up benefits in well-being. Psychother Psychosom. 2007;76:226–33.