In a review completed by Tracey
(2002) the relationship between inflammation and the nervous system is
discussed. Inflammation is a protective response in the body that requires
precise regulation. Cholinergic neurons can prevent inflammation, which
suggests that the nervous system is vital in our immune responses to our
environment. The nervous system can gather information from the internal environment
and respond by inhibiting systemic cytokines such as TNF, which mediates
subsequent cascades of cytokines. The communication between the nervous system
and immune response is dynamic, meaning cytokines can be released through the
HPA axis. Additionally, the immune
system has the capacity to synthesize neuropeptides such as acetylcholine and
other neurotransmitters.
Tracey, K. J. D. a-D.
19-26 D. O.-10. 1038/Nature0132. N. [Pii] D. P.-N. L. M. E. T.-2002/12/20.
(2002). The inflammatory reflex. Nature, 420(December), 853–9
ST – The inflammatory reflex.
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