Melatonin Exerts Growth Inhibition in Breast Cancer Cells

A meta-analysis of randomized controlled trials examines the efficacy and safety of melatonin in concurrent chemotherapy or radiotherapy for solid tumors.  Wang et al (2012) discusses both in vitro and in vivo investigations of how melatonin protects healthy cells from radiation and chemotherapy toxicity.  Melatonin was found to be effective in suppressing the growth of tumors and decreasing the side effects of radiation and chemotherapy.  It is also noted that additional research (see citations) has found melatonin to be effective in suppressing tumor growth in a variety of cancers such as melanoma, breast, prostate, ovarian, and colorectal cancer.

See the entire article @ SpringerLink: CANCER CHEMOTHERAPY AND PHARMACOLOGY